El Angiofibroma nasofaríngeo juvenil es un tumor benigno vascular (pero que tardíamente Se localiza en la pared posterolateral de la grita nasal a nivel del vínculo de la apófisis esfenoidal del hueso palatino. Esta localización conforma el. Nasal cavity, paranasal sinuses, nasopharynx – Nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally in the nasopharynx and nasal cavity, leading to manifestations such as nasal.

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Steroid hormone receptor expression in nasopharyngeal angiofibromas.

Nasopharyngeal angiofibroma – Wikipedia

JNA being an aggressive tumor may recur posttreatment. Edit article Share article View revision history. Of the 20 patients, 3 had surgery by combined approaches conventional and endoscopicincluding 1 patient with a Fisch IIIA jyvenil who was treated by the Caldwell-Luc expanded technique and endoscopic surgery, 1 patient with a Fisch IIIA tumor who was treated by the degloving mid-facial technique and endoscopic surgery, and 1 with a Fisch IV tumor who was treated by the degloving mid-facial technique associated with craniotomy and endoscopic surgery.

Received Jul 15; Accepted Juvvenil 1.

Juvenile nasopharyngeal angiofibroma

Treatment trends in patients during 40 years. IIb Full occupation of the pterygomaxillary fossa, anterior displacement of the posterior wall of the maxillary antrum. The remaining 17 patients, regardless of the tumor classification, underwent embolization and clamping of the external carotid arteries due to better control of bleeding during surgery.

Fisch classification, however, is currently accepted. Detection of residual tumor on postoperative follow-up was the criterion for reoperation. Same as Ia, but with extension into one or more paranasal sinuses. Some authors maintain that endoscopic approaches should only be used when the tumor is confined to the nasal cavity, paranasal sinuses, pterygopalatine fossa, or infratemporal fossa.

Blood vessels were seen in large number at the periphery of the lesion [ Figure 5 ]. Endoscopic surgery was performed in three patients, without postoperative complications; endoscopic-assisted surgery in three others, with two instances of complications, and external surgery in seven.


Any lesion with this presentation may be confused with JNA. We analyzed 20 patients with nasopharyngeal angiofibroma who underwent surgery in the otolaryngology service between and The tumor is primarily excised by external or endoscopic approach. The classification and clinical staging is relatively angiofibfoma and helps to plan treatment and determine prognosis.

ChildhoodAdolescent ICD Electron dense granules composed of tightly bound RNA protein complexes Stromal cells are myofibroblasts. Medical treatment and radiation therapy are only of historical interest.

Analysis of these 13 patients suggests that fully endoscopic surgery is viable even in advanced cases of JNA. Synonyms or Alternate Spellings: Naal Read Edit View history.

We analyzed findings in 20 patients who underwent surgery between and In addition, preoperative embolization may complicate the identification of the full extent of surgical margins by reducing the tumor size and increasing the risk of relapse Continuous growth involves the sphenoidal sinus, nasal fossa and middle turbinate, pterygomaxillary fossa and the posterior wall of the maxillary sinus as seen in the present case.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Results Thirteen patients met the criteria for inclusion and underwent surgical treatment. InFriedberg called it juvenile angiofibroma.

Read it at Google Books – Find nassal at Amazon. Mortality is not associated with nasopharyngeal angiofibroma. Surgery of cranial base tumors. Classification of Fisch Type Nsal Non-small-cell lung carcinoma Squamous-cell carcinoma Adenocarcinoma Mucinous cystadenocarcinoma Large-cell lung carcinoma Rhabdoid carcinoma Sarcomatoid carcinoma Carcinoid Salivary gland—like carcinoma Adenosquamous carcinoma Papillary adenocarcinoma Giant-cell carcinoma.

Invasion of the intracranial region may lead to cranial nerve palsy. Clinical examination reveals a firm and friable mass in the nasopharynx and nose. Because these tumors are benign, metastasis to distal sites does not occur.


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Orphanet: Angiofibroma nasofar ngeo juvenil

The mean operation time was min, and the mean bleeding volume was mL. CT images show a heterodense mass that is centered in the sphenopalatine foramen.

Clinically, however, it is obscure with painless, progressive unilateral nasal obstruction being the common presenting symptom with or without epistaxis and rhinorrhea. JNA classically presents as a painless, progressive unilateral nasal obstruction.

Nasopharyngeal angiofibroma

Juveni treatments are available, including the use of hormones estrogen, testosteroneradiation therapy, chemotherapy, and recently, embolization; however, surgery is considered the treatment of choice, with the route depending on the stage of the tumor and the overall condition of the patient 11,12, Many studies highlight the benefit of preoperative arterial embolization to control bleeding intraoperative 16,29, Plain radiographs no longer play a role in the workup of a suspected juvenile nasopharyngeal angiofibroma, however they may still be obtained in some instances during the assessment of nasal obstruction, or symptoms of sinus obstructions.

Otolaryngol Head Neck Surg.

The limitations of the present study should also be considered. According to the adopted categorization scheme, these patients would correspond to grade IIIb of the Andrews classification. Invading the pterygopalatine fossa or the maxillary, ethmoid, or sphenoid sinus with bone destruction. All 20 patients jjuvenil available for follow-up maximum, 7 yearswith none showing evidence of tumor recurrence.

Axial section in computed tomography demonstrating obliteration of the nasal cavity and maxillary sinus.