Erythema elevatum diutinum (EED) is a rare, chronic dermatosis that is characterized by red–violet to red–brown papules, plaques, and. Erythema elevatum diutinum (EED) is a chronic form of leukocytoclastic vasculitis consisting of violaceous, red-brown, or yellowish papules. Erythema elevatum diutinum. Authoritative facts about the skin from DermNet New Zealand.

Author: Tasho Mezshura
Country: Armenia
Language: English (Spanish)
Genre: Video
Published (Last): 28 April 2016
Pages: 302
PDF File Size: 10.5 Mb
ePub File Size: 4.10 Mb
ISBN: 913-2-87224-733-9
Downloads: 67677
Price: Free* [*Free Regsitration Required]
Uploader: Juzragore

There is still controversy about the etiology of EED. Images hosted on other servers: J Am Acad Dermatol. Sign in via Shibboleth.

Eritema elevatum diutinum | Actas Dermo-Sifiliográficas

Andrews’ Diseases of the Skin: We report three cases of erythema elevatum diutinum. Electron microscopy is not a necessary diagnostic tool but would show changes and features of leukocytoclastic vasculitis. When there is a diagnosis of erythema elevatum diutinum, HIV infection should be investigated, especially in atypical and exacerbated clinical manifestations. Clinically is characterized by red, purple, brown or yelow papules, plaques or nodules.

Diutknum, the most widely accepted theory is that previous and repeated exposure to bacterial infections, particularly streptococcal ones, may trigger an immunological reaction elevayum culminates in an outbreak of skin lesions. Indian Dermatol Online J. The condition is benign in nature but may be associated with infections, hematologic abnormalities, autoimmune diseases, or other conditions. Venous ulcer Arterial insufficiency ulcer Hematopoietic ulcer Neuropathic ulcer Acroangiodermatitis.

Erythema elevatum diutinum and IgA myeloma: Erythema Diiutinum Diutinum [Accessed 30 August ]. These lesions are usually symmetrically distributed on the extensor surfaces of the extremities.


Over time, the infiltrate contains more histiocytes and granulation tissue, and spindle cell proliferation may be seen.

To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. It is generally associated with autoimmune, neoplastic and infectious processes. Erythema gyratum repens Necrolytic migratory erythema. Accessed December 31, You can change the settings or obtain more information by clicking here. Erythema elevatum diutinum and HIV infection: Bilaterally symmetric erythematous or violaceous plaques or nodules, often over outer surface of joints Systemically ill patients or associated with HIV May be related to granuloma faciale May be an immune-complex vasculitis eritemq by chronic antigen exposure.

Etiology The cause of EED is not well understood, but it is thought to be secondary to immune complex deposition in dermal blood vessels, which results in complement fixation and subsequent inflammation. Cutaneous vasculitis and other vascular-related cutaneous conditions L95 Antineutrophil cytoplasmic antibodies ANCA of the immunoglobulin G IgG type have proven useful for the diagnosis and monitoring of disease activity in various systemic vasculitides, including granulomatosis with polyangiitis Wegener’smicroscopic polyangiitis MPOpolyarteritis nodosa, and Churg—Strauss syndrome.

Erythema elevatum diutinum

It presents predominantly in males, in the fourth to sixth decade of life. Dapsone, a sulfonamide antibiotic that impairs neutrophil chemotaxis and function, is the most effective treatment agent, but relapse is common upon discontinuation. Erythema elevatum diutinum diutinun a rare and chronic skin disorder. EED is classified as a small vessel vasculitis.


diitinum Localized chronic fibrosing vasculitis: EED is a chronic and progressive skin disease that may last as long as 25 years.

Dermatologic conditions reported in patients with rheumatoid arthritis. The cause of EED is not yet defined, but it has been associated with the following conditions:. The incidence of EED is unknown; however, it appears to diutinun a rare disease. It is also supposed that the immunosuppression caused by HIV predisposes towards infection by other agents that trigger an antigenic stimulus for the development of EED.

Erythema elevatum diutinum is a form of vasculitis. This cutaneous condition article is a stub. Furthermore, the initiation of EED may occur via activation of cytokines interleukin-8which causes selective recruitment of leukocytes to blood vessels. It occurs equally in men and women.

The male-to-female ratio is approximately equal, and no racial predilection has been observed. Si continua navegando, consideramos que acepta su uso. National Center for Biotechnology InformationU. Erythema elevatum diutinum in association with coeliac disease.

None Date of first submission: